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2.
Arq. neuropsiquiatr ; 78(12): 778-782, Dec. 2020. tab
Article in English | LILACS | ID: biblio-1142370

ABSTRACT

ABSTRACT Background: Migraine is one of the most common disorders in neurological clinical practice and is part of the group of primary headaches. It often affects individuals in the age group of 25-55 years, when people are at their peak of economic productivity. Many patients ultimately overuse analgesics. Overuse is defined by the use of analgesics for at least 15 times a month - within a minimal three-month period. Impulsivity and migraine cause losses in the lives of individuals suffering from them, as they can compromise these individuals' social, emotional, and professional spheres. Regarding the professional sphere, it results in economic losses compared with the overall population. Objective: To investigate the presence of impulsive behavior in patients with migraine and with medication-overuse migraine. Methods: Cross-sectional study on 210 female and male patients; 140 were diagnosed with migraine according to criteria of the International Classification of Headache Disorders and were subdivided into two groups (70 patients each). One of these groups was composed of medication-overuse patients; the control group was composed of non-migraine patients (70 patients). All patients were evaluated with the Barratt Impulsivity Scale (BIS-11). Results: The group of migraine patients accounted for the highest impulsivity level, followed by the control group and, finally, by the medication-overuse group. However, these differences did not attain statistical significance. Conclusions: It was not possible to establish a clear connection between migraine and impulsive behavior. Association was higher among migraineurs without medication overuse.


RESUMO Introdução: A enxaqueca é uma das condições mais comuns na prática clínica neurológica, enquadrando-se no grupo das cefaleias primárias. Sua prevalência é maior na faixa etária de 25 a 55 anos, coincidindo com o pico da produtividade econômica. Muitos pacientes recorrem ao uso abusivo de analgésicos. O uso excessivo desses medicamentos é definido pela sua utilização por pelo menos 15 vezes ao mês, por um período de no mínimo três meses. A impulsividade e a enxaqueca causam prejuízos na vida dos indivíduos afetados, podendo comprometer os âmbitos social, emocional e profissional, resultando em um prejuízo monetário a esse grupo, em relação à população em geral. Objetivo: Investigar a presença de comportamento impulsivo em pacientes com enxaqueca com abuso de analgésico. Métodos: Estudo de corte transversal com 210 pacientes, homens e mulheres, sendo 140 com diagnóstico de enxaqueca segundo os critérios da Classificação Internacional das Cefaleias (IHCD-3), subdivididos em dois grupos de 70 pacientes cada, um composto por pacientes em uso excessivo de medicamentos, e um grupo controle composto por indivíduos sem enxaqueca. Todos os pacientes foram avaliados com a Escala de Impulsividade de Barratt - BIS 11. Resultados: O grupo com enxaqueca apresentou maior impulsividade, seguido do grupo controle e, por fim, o grupo com enxaqueca com abuso de medicamentos. No entanto, essas diferenças não atingiram significância estatística. Conclusão: Não foi possível encontrar relação direta entre a enxaqueca e comportamentos impulsivos. No entanto, esta relação foi maior entre os pacientes com enxaqueca sem abuso de analgésico.


Subject(s)
Humans , Male , Female , Adult , Middle Aged , Headache Disorders, Secondary/epidemiology , Migraine Disorders/drug therapy , Migraine Disorders/epidemiology , Prevalence , Cross-Sectional Studies , Prescription Drug Overuse , Analgesics/adverse effects , Impulsive Behavior
4.
Arq. neuropsiquiatr ; 78(3): 133-138, Mar. 2020. tab
Article in English | LILACS | ID: biblio-1098078

ABSTRACT

Abstract Cognitive impairment has been described in all phases of a migraine attack and interictally. However, the prevalence and phenotype of such impairment in chronic migraine (CM) have not yet been studied. Objectives: The aim of this study was to evaluate both the prevalence of the objective cognitive deficit in patients with CM and the factors underlying its etiology. Methods: 144 patients with CM and 44 age-matched patients with low-frequency episodic migraine (EM) (a maximum of 4 headache days per month) participated in this study. Neuropsychiatric characteristics were measured with the HADS Hospital Anxiety and Depression Scale. Cognitive function was assessed with the Montreal Cognitive Assessment (MoCA), Digit Symbol Substitution Test (DSST), Rey Auditory Verbal Learning Test (RAVLT), and the Perceived Deficits Questionnaire (PDQ-20). Results: Compared to EM, CM subjects demonstrated higher subjective and objective cognitive impairment across all tests. CM patients had 4 times higher odds of achieving a RAVLT score in the lower quartile range compared to EM (Odds Ratio [OR] 3.8; 95% confidence interval [95%CI] 1.5‒9.6; р=0.005). In the MoCA, CM patients demonstrated the most striking impairment in memory/delayed recall (65.3%), attention (46.5%), abstraction (30.6%), and language (27.1%). Chronic headache and level of education, but not gender, depression or anxiety, were independent predictors of cognitive impairment. Conclusions: Cognitive impairment is prevalent in the CM population during their mildest possible pain and may be caused by a central sensitization. Timely preventive treatment of EM is warranted.


Resumo O comprometimento cognitivo foi descrito em todas as fases de um ataque de enxaqueca, de maneira intermitente. Entretanto, a prevalência e o fenótipo desse comprometimento na enxaqueca crônica (EC) não foram estudados. Objetivos: O objetivo deste estudo foi avaliar a prevalência do déficit cognitivo objetivo em pacientes com EC e fatores subjacentes à sua etiologia. Métodos: 144 pacientes com CM e 44 pacientes pareados por idade com enxaqueca episódica (EE) de baixa frequência (máximo de 4 dias de dor de cabeça por mês) foram incluídos. As características neuropsiquiátricas foram medidas pela Hospital Anxiety and Depression Scale (HADS). A função cognitiva foi avaliada por meio da Montreal Cognitive Assessment (MoCA), o Digit Symbol Substitution Test (DSST), o Rey Auditory Verbal Learning Test (RAVLT) e o Perceived Deficits Questionnaire (PDQ-20). Resultados: Em comparação com a EE, os indivíduos com EC demonstraram um comprometimento cognitivo subjetivo e objetivo maior em todos os testes. Os pacientes com CM tiveram 4 vezes mais chances de alcançar um escore RAVLT na faixa quartil inferior, em comparação com EE (Odds Ratio [OR] 3,8; intervalo de confiança de 95% [IC95%] 1,5‒9,6; p=0,005). No MoCA, os pacientes com EC demonstraram o maior prejuízo na memória/atraso na recordação (65,3%), atenção (46,5%), abstração (30,6%) e linguagem (27,1%). Dor de cabeça crônica e nível de escolaridade, mas não o sexo, depressão ou ansiedade, foram preditores independentes de comprometimento cognitivo. Conclusões: O comprometimento cognitivo é prevalente na população com enxaqueca crônica mesmo durante uma dor muito leve e pode ser causado pela sensibilização central. O tratamento preventivo oportuno da enxaqueca episódica se faz necessário.


Subject(s)
Humans , Male , Female , Adult , Middle Aged , Cognitive Dysfunction/etiology , Headache/epidemiology , Migraine Disorders/epidemiology , Anxiety/epidemiology , Severity of Illness Index , Prevalence , Cross-Sectional Studies , Depression/physiopathology , Depression/epidemiology , Cognitive Dysfunction/psychology , Cognitive Dysfunction/epidemiology , Migraine Disorders/classification , Migraine Disorders/psychology
5.
Arq. neuropsiquiatr ; 77(9): 617-621, Sept. 2019. tab
Article in English | LILACS | ID: biblio-1038747

ABSTRACT

ABSTRACT Migraine adds to the burden of patients suffering from multiple sclerosis (MS). The ID-migraine is a useful tool for screening migraine, and the Migraine Disability Assessment questionnaire can evaluate disease burden. The aim of the present study was to assess the presence and burden of migraine in patients with MS. Methods: Patients diagnosed with MS attending specialized MS units were invited to answer an online survey if they also experienced headache. Results: The study included 746 complete responses from patients with MS and headache. There were 625 women and 121 men, and 69% of all the patients were aged between 20 and 40 years. Migraine was identified in 404 patients (54.1%) and a moderate-to-high burden of disease was observed in 68.3% of the patients. Conclusion: Migraine is a frequent and disabling type of primary headache reported by patients with MS.


RESUMO Enxaqueca piora o sofrimento do paciente que tem esclerose múltipla (EM). ID-migraine é uma ferramenta útil para seleção de pacientes com enxaqueca e Migraine Disability Assessment (MIDAS) é um questionário que avalia o impacto da doença. O objetivo do presente estudo foi avaliar a presença e impacto de enxaqueca em pacientes com EM. Métodos: Pacientes diagnosticados com EM e tratados em clínicas especializadas foram convidados a responder um questionário online se também apresentassem cefaleia. Resultados: O estudo incluiu 746 participantes com cefaleia e EM que preencheram completamente as respostas. Foram 625 mulheres e 121 homens, sendo 69% dos pacientes com idade entre 20 e 40 anos. Enxaqueca foi identificada em 404 pacientes (54,1%) e moderado a grave impacto da doença foi observado em 68,3% dos casos. Conclusão: Enxaqueca é uma cefaleia primária frequente e incapacitante relatada por pacientes com EM.


Subject(s)
Humans , Male , Female , Adult , Young Adult , Headache/epidemiology , Migraine Disorders/epidemiology , Multiple Sclerosis/epidemiology , Brazil/epidemiology , Prevalence , Cross-Sectional Studies , Surveys and Questionnaires , Treatment Outcome , Sex Distribution , Disability Evaluation , Headache/drug therapy , Migraine Disorders/drug therapy
6.
Biomédica (Bogotá) ; 39(supl.2): 93-100, ago. 2019. tab, graf
Article in Spanish | LILACS | ID: biblio-1038831

ABSTRACT

RESUMEN Introducción. La patogenia de los trastornos funcionales gastrointestinales involucra agentes infecciosos como los virus. Objetivo. Investigar el desarrollo de trastornos funcionales gastrointestinales en niños, a los 3, 6, 9 y 12 meses después de un episodio de dengue no grave sin signos de alarma. Materiales y métodos. Se hizo un estudio de cohorte de 73 niños con diagnóstico de dengue no grave sin signos de alarma atendidos en el Hospital Universitario del Valle "Evaristo García" y de 62 niños sanos de Cali, Colombia. Mediante el 'Cuestionario para síntomas gastrointestinales pediátricos Roma III' (Questionnaire for Pediatric Gastrointestinal Symptoms Rome III, QPGS-III), se determinaron los trastornos gastrointestinales funcionales a los 3, 6, 9 y 12 meses de seguimiento después de un episodio de dengue no grave sin signos de alarma. Se calcularon las medidas de tendencia central, riesgo relativo y prueba de ji al cuadrado, y se usó la prueba exacta de Fisher con un nivel de significación (p) menor de 0,05. Resultados. Se incluyeron 135 niños de 10,7±1,9 años; 51,1 % de ellos correspondía al sexo masculino y 19,3 % presentaba algún trastorno funcional gastrointestinal (9,6 % con dolor abdominal relacionado). El riesgo de presentar algún trastorno funcional gastrointestinal con dolor abdominal relacionado a los 3, 6, 9 y 12 meses de seguimiento en niños con dengue no grave sin signos de alarma fue mayor que sin dicho antecedente, pero sin diferencias significativas. Conclusión. Los resultados del estudio sugieren que el dengue no grave sin signos de alarma no incrementó el riesgo de trastornos gastrointestinales funcionales y dolor abdominal relacionado a lo largo de 12 meses de seguimiento.


ABSTRACT Introduction: The pathogenesis of functional gastrointestinal disorders involves infectious agents such as viruses. Objective: To study the development of functional gastrointestinal disorders 3, 6, 9 and 12 months after an episode of non-severe dengue without warning signs in children. Materials and methods: We conducted a cohort study in 73 children diagnosed with non-severe dengue without warning signs at Hospital Universitario del Valle "Evaristo García" and 62 healthy children from Cali, Colombia. Using the Questionnaire for Pediatric Gastrointestinal Symptoms Rome III (QPGS-III) in Spanish we identified functional gastrointestinal disorders 3, 6, 9, and 12 months after non-severe dengue without warning signs. Measurements of central tendency, relative risk, chi square, and Fisher's exact test were performed, with p<0.05 being significant. Results: We included 135 children who were 10.7±1.9 years old; 51.1% of them were male and 19.3% had a functional gastrointestinal disorder (9.6% of them had abdominal pain related to functional gastrointestinal disorders). There was a greater risk to present a functional gastrointestinal disorder and related abdominal pain in children after non-severe dengue without warning signs at 3, 6, 9, and 12 months of follow-up, but without significant differences. Conclusion: Our study suggests that non-severe dengue without warning signs does not increase the risk of functional gastrointestinal disorders and related abdominal pain for up to 12 months of follow-up.


Subject(s)
Adolescent , Child , Female , Humans , Male , Dengue/complications , Gastrointestinal Diseases/etiology , Time Factors , Abdominal Pain/etiology , Surveys and Questionnaires , Cohort Studies , Dyspepsia/etiology , Dyspepsia/epidemiology , Gastrointestinal Diseases/epidemiology , Migraine Disorders/etiology , Migraine Disorders/epidemiology
9.
Braz. oral res. (Online) ; 32: e77, 2018. tab, graf
Article in English | LILACS | ID: biblio-952154

ABSTRACT

Abstract Temporomandibular disorders (TMD) are a highly prevalent, painful musculoskeletal condition affecting the masticatory system, and are frequently associated with migraines (M) and other diseases. This study aimed to investigate the association between painful TMD and M with other painful conditions and systemic diseases, such as cervicalgia, body pain (BP), ear-nose-throat disorders, musculoskeletal disorders, diabetes, cardiopulmonary diseases and gastritis/peptic ulcer. Methods: This was a cross-sectional study conducted in a sample of 352 individuals. Participants were stratified into three groups according to the presence of painful TMD and M: controls [individuals free of TMD and any headache (HA)]; TMD only (presence of painful TMD, but free of any HA); and TMD+M (presence of painful TMD and M). TMD was classified according to the Research Diagnostic Criteria for Temporomandibular Disorders (RDC/TMD) - Axis I. Nonspecific physical symptoms (NSPS) were assessed by RDC/TMD - Axis II. The International Classification of Headache Disorders - II criteria, second edition, were applied to identify and classify primary HA. Other painful conditions and systemic diseases were assessed by volunteers' self-report. The prevalence of all assessed conditions was higher in the TMD+M group. Multiple regression models showed that cervicalgia was associated with the TMD only group (p<0.05), whereas gender (p<0.05), cervicalgia (p<0.05), BP (p<0.05) and NSPS (p<0.05) were significantly associated with the TMD+M group. Our results suggest that individuals with a comorbidity (TMD associated with M) have a more severe condition than those presenting only painful TMD.


Subject(s)
Humans , Male , Female , Adolescent , Adult , Aged , Young Adult , Facial Pain/epidemiology , Temporomandibular Joint Disorders/epidemiology , Migraine Disorders/epidemiology , Peptic Ulcer/physiopathology , Peptic Ulcer/epidemiology , Facial Pain/physiopathology , Brazil/epidemiology , Temporomandibular Joint Disorders/physiopathology , Comorbidity , Logistic Models , Sex Factors , Prevalence , Cross-Sectional Studies , Musculoskeletal Diseases/physiopathology , Musculoskeletal Diseases/epidemiology , Neck Pain/physiopathology , Neck Pain/epidemiology , Diabetes Complications/physiopathology , Diabetes Mellitus/physiopathology , Diabetes Mellitus/epidemiology , Gastritis/complications , Gastritis/physiopathology , Gastritis/epidemiology , Middle Aged , Migraine Disorders/physiopathology
10.
Article in Spanish | LILACS | ID: biblio-908133

ABSTRACT

Introducción: la migraña vestibular definida es una de las causas más comunes de vértigo, así como el vértigo paroxístico benigno e hidrops endolinfático. Su prevalencia en la población general se ha estimado entre 1,1 a 3,2%. En Latinoamérica son pocos los estudios acerca de las características epidemiológicas y las comorbilidades adjuntas de los pacientes con diagnóstico de migraña vestibular. Este trabajo describe la correlación entre las características epidemiológicas y las comorbilidades adjuntas de los pacientes evaluados por migraña vestibular definida en el Hospital Británico de Buenos Aires en el periodo comprendido entre enero de 2014 y febrero de 2016. Materiales y métodos: Se realizó un estudio observacional descriptivo retrospectivo con revisión manual de historias clínicas de pacientes evaluados en la consulta de otorrinolaringología. Resultados: El estudio mostró que la edad media de los pacientes con migraña vestibular definida fue 44,4 años, observándose mayor número de consultas por pacientes del sexo femenino. Las comorbilidades no otoneurológicas más frecuentes encontradas en el sexo masculino fueron epilepsia y diabetes mellitus tipo II y en el sexo femenino depresión. La comorbilidad otoneurológica más frecuentemente encontrada tanto en el sexo masculino como femenino fue hidrops endolinfático. Conclusiones: En la población las consultas fueron en mayor número de mujeres con una edad media de 44,4 años. Las comorbilidades no otoneurológicas encontradas en hombres fueron epilepsia y diabetes mellitus tipo II y en mujeres depresión. La comorbilidad otoneurológica más encontrada tanto en hombres como en mujeres fue hidrops endolinfático.


Introduction: defined Migraine associated- vertigoisone of the most common etiologies of vertigo as peripheric benign vertigo and endolympatic hydrops are. Its prevalence on population is estimated between 1.1 to 3.2%. In Latin America there are few studies about epidemiologic characteristics and comorbidities of diagnosed patients with defined migraine associated vertigo. This work describes the relationship between the epidemiologic characteristics and the comorbidities of patients evaluated for defined migraine associated vertigo at Buenos Aires British Hospital since january 2014 to february 2016. Methods: An observational, descriptive and retrospective study was done. Clinical records of otolaryngology consult were reviewed. Results: This study showed a mean age of 44.4 years old for the patients of defined migraine associated vertigo, the majority of consults were done for female gender. The most common non – neurotological comorbidities found in male gender were epilepsy and diabetes mellitus type II and in female gender was depression. The most common neurotological condition found in female and male gender was endolympatic hydrops. Conclusions: The majority of consults were achieved by female population with a mean age of 44.4 years old. Non-neurotological comorbidities found in men were epilepsy and diabetes mellitus type II and in women depression. The most common neurotological comorbidity found in men and women was endolymphatic hydrops.


Introdução: a enxaqueca vestibular definitiva é uma das causas mais comuns de vertigem e vertigem paroxística benigna e hidropisia endolinfática. A sua prevalência na população em geral tem sido estimado entre 1,1 e 3,2%. Na América Latina existem poucos estudos sobre a epidemiologia e as co-morbidades que acompanham de pacientes com diagnóstico de enxaqueca vestibular. Este artigo descreve a correlação entre as características epidemiológicas e as co-morbidades que acompanham de pacientes avaliados para a enxaqueca vestibular definidos no Hospital Britânico de Buenos Aires no período compreendido entre Janeiro de 2014 e Fevereiro de 2016. Materiais e métodos: um estudo observacional retrospectivo com revisão manual dos prontuários de pacientes avaliados em consulta de otorrinolaringologia foi realizado. Resultados: O estudo mostrou que a idade média dos pacientes com enxaqueca vestibular definitiva foi de 44,4 anos, mostrando mais consultas por parte de pacientes do sexo feminino. As comorbidades mais freqüentes não otoneurológicas encontrados nos machos foram epilepsia e diabetes mellitus tipo II e depressão em mulheres. A comorbidade otoneurológico mais frequentemente encontrado em ambos os sexos masculino e feminino foi hidropisia endolinfática. Conclusões: na população nas consultas eram mais mulheres com uma idade média de 44,4 anos. Os homens não otoneurológicas comorbidades foram encontrados em epilepsia e diabetes mellitus tipo ii depressão e mulheres. Quanto mais comorbidade otoneurológico encontrados em homens e mulheres era de hidropisia endolinfática.


Subject(s)
Male , Female , Humans , Adolescent , Adult , Young Adult , Middle Aged , Aged , Aged, 80 and over , Comorbidity , Migraine Disorders/complications , Migraine Disorders/epidemiology , Benign Paroxysmal Positional Vertigo , Endolymphatic Hydrops , Vertigo , Vestibular Diseases/epidemiology
11.
Arq. neuropsiquiatr ; 74(12): 999-1002, Dec. 2016. tab
Article in English | LILACS | ID: biblio-828004

ABSTRACT

ABSTRACT Objective To assess the prevalence of headache in post-menopausal women. Methods Women attending gynecology outpatient services in the coastal region of the state of Sao Paulo, Brazil were invited to participate in this study. Only those with non-surgical menopause and no hormone replacement therapy were included. Prevalence and characterization of headaches were assessed, as well as the burden of migraine, traits of anxiety and depression, and menopausal symptomatology. Results One hundred and three women were included in the study. Migraine affected 14.7% of them. Some previous type of headache was reported by 86.2% of the women, most of whom improved during menopause but still presented with headache attacks. There was a correlation between higher migraine disability and depressive traits. Conclusions Many women believe that their headaches, particularly migraine, will end after menopause. This is, unfortunately, not the case for many of them.


RESUMO Objetivo Avaliar a prevalência de cefaleia em mulheres no período pós-menopausal. Métodos Mulheres atendidas em serviços de ginecologia na região costeira do estado de São Paulo, Brasil foram convidadas a participar deste estudo. Apenas mulheres com menopausa não-cirúrgica e sem terapia de reposição hormonal foram incluídas. Foram avaliados prevalência e características das cefaleias, incapacidade por enxaqueca, traços de ansiedade e depressão e sintomatologia menopausal. Resultados Centro e três mulheres foram incluídas neste estudo. Enxaqueca afetava 14,7% delas. Antecedente de algum tipo de dor de cabeça foi relatada por 86,2% das mulheres, a maioria das quais melhorou durante a menopausa, mas ainda apresentava crises. Houve correlação entre maior incapacidade por enxaqueca e traço depressivo. Conclusão Muitas mulheres acreditam que suas cefaleias, particularmente enxaqueca, terminarão quando começar a menopausa. Este, infelizmente, não é o caso para muitas delas.


Subject(s)
Humans , Female , Middle Aged , Postmenopause/psychology , Mood Disorders/epidemiology , Migraine Disorders/epidemiology , Anxiety/epidemiology , Social Class , Severity of Illness Index , Brazil/epidemiology , Postmenopause/physiology , Age of Onset , Depression/epidemiology
12.
Braz. j. otorhinolaryngol. (Impr.) ; 82(4): 397-402, July-Aug. 2016. tab, graf
Article in English | LILACS | ID: lil-794990

ABSTRACT

ABSTRACT INTRODUCTION: Vestibular migraine (VM) is one of the most often common diagnoses in neurotology, but only recently has been recognized as a disease. OBJECTIVE: To analyze the clinical and epidemiological profile of patients with VM. METHODS: This was a retrospective, observational, and descriptive study, with analysis of patients' records from an outpatient VM clinic. RESULTS: 94.1% of patients were females and 5.9% were males. The mean age was 46.1 years; 65.6% of patients had had headache for a longer period than dizziness. A correlation was detected between VM symptoms and the menstrual period. 61.53% of patients had auditory symptoms, with tinnitus the most common, although tonal audiometry was normal in 68.51%. Vectoelectronystagmography was normal in 67.34%, 10.20% had hyporeflexia, and 22.44% had vestibular hyperreflexia. Electrophysiological assessment showed no abnormalities in most patients. Fasting plasma glucose and glycemic curve were normal in most patients, while the insulin curve was abnormal in 75%. 82% of individuals with MV showed abnormalities on the metabolism of carbohydrates. CONCLUSION: VM affects predominantly middle-aged women, with migraine headache representing the first symptom, several years before vertigo. Physical, auditory, and vestibular evaluations are usually normal. The most frequent vestibular abnormality was hyperreflexia. Most individuals showed abnormality related to carbohydrate metabolism.


Resumo Introdução: Migrânea vestibular (MV) corresponde a um dos mais frequentes diagnósticos em otoneurologia, o que justifica a importância de seu estudo, embora tenha sido apenas recentemente reconhecida como entidade nosológica. Objetivo: Analisar os perfis clínico e epidemiológico dos pacientes atendidos em um ambulatório de migrânea vestibular. Método: Estudo retrospectivo, observacional e descritivo, com análise de prontuários dos pacientes do ambulatório de MV. Resultados: O ambulatório é composto por 94,1% de mulheres e 5,9% de homens, com média de idade 46,1 anos. O tempo de cefaleia foi superior ao de vertigem em 65,6% dos pacientes. Observou-se correlação entre os sintomas e o período menstrual. A maioria (61,53%) dos indivíduos apresentou algum sintoma auditivo, sendo o zumbido o mais frequente, embora a audiometria tenha sido normal em 68,51%. A vectoeletronistagmografia apresentou-se normal em 67,34%, enquanto 10,20% apresentaram hiporreflexia e 22,44% hiperreflexia vestibular. Exames eletrofisiológicos não mostraram alterações na maioria dos pacientes. Glicemia dejejum e curva glicêmica foram normais para a maioria dos pacientes, enquanto a curva insulinêmica mostrou-se alterada em 75% dos indivíduos. 82% dos indivíduos com MV apresentaram alguma alteração relativa ao metabolismo dos carboidratos. Conclusão: Migrânea vestibular acomete, predominantemente, mulheres de meia idade, com cefaleia migranosa e vertigem, sendo a primeira de instalação mais precoce. O exame físico no período intercrise, bem como as avaliações auditiva e vestibular, mostram-se, geralmente, normais. O tipo de alteração vestibular mais observado foi a hiperreflexia labiríntica. A maioria os indivíduos avaliados apresentou alterações relativas ao metabolismo dos carboidratos.


Subject(s)
Humans , Male , Female , Adult , Middle Aged , Aged , Young Adult , Vestibular Diseases/epidemiology , Migraine Disorders/epidemiology , Audiometry, Pure-Tone , Vestibular Function Tests , Brazil/epidemiology , Vestibular Diseases/diagnosis , Cross-Sectional Studies , Retrospective Studies , Vestibular Evoked Myogenic Potentials , Migraine Disorders/diagnosis
13.
Arq. neuropsiquiatr ; 73(12): 1009-1013, Dec. 2015. tab, graf
Article in English | LILACS | ID: lil-767618

ABSTRACT

ABSTRACT Objective To evaluate the prevalence of headache in medical students, and quantify the degree of disability through HIT-6 and MIDAS scale. Method The criteria established by International Headache Society were used and the HIT-6 and MIDAS, to asses disability. Results 140 medical students from UFAM were evaluated. 16.43% cases of migraine headache, 6.43% of probable migraine, and 23.57% of tension headaches were detected. 6.42% reported an absence of headache; and another 11.42% had secondary headache. According to the HIT-6 questionnaire, in 7.14% and 18.57% of the students, headaches were classified as having substantial to severe impact, respectively. Conclusion Migraine and probable migraine had higher scores than the other types of headache and, therefore, led to higher levels of disability. The present study did not find a significant correlation between student semester, age or extracurricular activities on the impact generated by headache.


RESUMO Objetivo Avaliar a prevalência de cefaleia em estudantes médicos e quantificar o grau de incapacidade através das escalas HIT-6 e MIDAS. Método Os critérios da Sociedade Internacional de Cefaleia foram usados e as escalas Hit-6 e MIDAS foram usadas para medir a incapacidade. Resultados 140 estudantes de medicina da UFAM foram avaliados. 16.43% eram migrânea, 6.43% de provável migrânea e 23.57% de cefaleia tipo tensional. 6,42% relataram ausência de cefaleia e 11.42% possuíam cefaleia secundária. De acordo com o questionário HIT-6 em 7,14% e 18,57% dos estudantes, a cefaleia foram classificadas como impacto substancial e grave respectivamente. Conclusão Migrânea e provável migrânea tiveram escores mais elevados do que os outros tipos de cefaleia e maiores níveis de incapacidade. O estudo não encontrou uma associação significante entre o período de graduação, idade ou das atividades extracurriculares com o impacto gerado pela cefaleia.


Subject(s)
Female , Humans , Male , Young Adult , Migraine Disorders/epidemiology , Students, Medical/statistics & numerical data , Brazil/epidemiology , Cross-Sectional Studies , Disability Evaluation , Headache Disorders/classification , Headache Disorders/epidemiology , Migraine Disorders/classification , Prevalence , Quality of Life , Severity of Illness Index , Surveys and Questionnaires
14.
Ciênc. Saúde Colet. (Impr.) ; 20(11): 3477-3486, Nov. 2015. graf
Article in Portuguese | LILACS | ID: lil-766401

ABSTRACT

Este estudo objetivou verificar a prevalência de cefaleia em adolescentes e sua associação com o uso excessivo de computador e jogos eletrônicos. A amostra foi composta por 954 adolescentes (14 a 19 anos), de ambos os sexos, que responderam ao questionário sobre uso de computadores e jogos eletrônicos, presença de cefaleia e atividade física. Foi utilizada a regressão logística binária e multinomial, com nível de significância de 5%. Evidenciou-se alta prevalência de cefaleia (80,6%) e elevado tempo de uso de dispositivos eletrônicos. O uso excessivo dos dispositivos eletrônicos mostrou-se fator de risco para cefaleia. Os sujeitos com idade entre 14 e 16 anos apresentaram menor chance de relatar a cefaleia. Em relação ao tipo, 17,9% apresentaram cefaleia do tipo tensional, 19,3% migrânea e 43,4% outros tipos de cefaleia. Os adolescentes com idade entre 14 e 16 anos apresentam menor chance de relatar a cefaleia do tipo tensional e de outros. Estar cursando o terceiro ano e usar excessivamente equipamentos digitais mostraram-se fatores de risco para cefaleia migrânea. Os resultados permitem concluir que o uso excessivo de dispositivos eletrônicos está associado à presença de cefaleia, principalmente do tipo migrânea.


The aim of this study was to determine the prevalence of headache in adolescents and its association with excessive use of electronic devices and games. The sample comprised 954 adolescents of both sexes (14 to 19 years) who answered a questionnaire about use of computers and electronic games, presence of headache and physical activity. The binary and multinomial logistic regression, with significance level of 5% was used for inferential analysis. The prevalence of headache was 80.6%. The excessive use of electronics devices proved to be a risk factor (OR = 1.21) for headache. Subjects aged between 14 and 16 years were less likely to report headache (OR = 0.64). Regarding classification, 17.9% of adolescents had tension-type headache, 19.3% had migraine and 43.4% other types of headache. The adolescents aged form 14 to 16 years had lower chance (OR ≤ 0.68) to report the tension-type headache and other types of headache. The excessive use of digital equipment, electronic games and attending the third year of high school proved to be risk factors for migraine-type development (OR ≥ 1.84). There was a high prevalence of headache in adolescents and high-time use of electronic devices. We observed an association between excessive use of electronic devices and the presence of headache, and this habit is considered a risk factor, especially for the development of migraine-type.


Subject(s)
Humans , Male , Female , Adolescent , Adult , Young Adult , Video Games , Headache/epidemiology , User-Computer Interface , Prevalence , Tension-Type Headache/epidemiology , Migraine Disorders/epidemiology
15.
Arq. neuropsiquiatr ; 73(7): 586-592, 07/2015. tab, graf
Article in English | LILACS | ID: lil-752379

ABSTRACT

Objective : To evaluate the use of analgesics in headache diagnosed in Outpatients Headache Clinic (ACEF), as well as his involvement in the activities of the patients. Method : 145 patients with headache seen at ACEF during the period August/July 2009/2010 underwent a questionnaire and interview with neurologist responsible for the final diagnosis according to ICHD-II. Results : Relationship Women:Men 7:1. 1) Prevalence: Migraine without aura (52.4%), migraine with aura (12.4%), chronic migraine (15.2%) and medication overuse headache (MOH) (20%). 2) Analgesic drugs used: Compounds with Dipyrone (37%), Dipyrone (23%), Paracetamol (16%) compound with Paracetamol (6%), triptans (6%) and non steroidal anti-inflammatory drugs (12%). There was a significant decrease in the duration of pain and less interference in the activities of the headache patients after the use of analgesics. Conclusion : Prevalence of MOH has been increasing in population level and specialized services. New studies emphasizing the MOH are needed to assist in the improvement of their diagnostic and therapeutic approach. .


Objetivo : Avaliar a utilização de analgésicos nas cefaleias diagnosticadas no Ambulatório de Cefaleias (ACEF), bem como a sua intervenção nas atividades dos pacientes. Método : 145 pacientes com cefaleia atendidos no ACEF durante o período entre Agosto/2009 a Julho/2010 foram submetidos a um questionário e à entrevista com médico neurologista responsável pelo diagnóstico final, segundo a ICHD-II. Resultados : Relação Mulheres:Homens de 7:1. 1) Prevalência: Migrânea sem aura (52,4%), migrânea com aura (12,4%), migrânea crônica (15,2%) e CEM (20%). 2) Analgésicos utilizados: Compostos com Dipirona (37%), Dipirona (23%), Paracetamol (16%), compostos com Paracetamol (6%), triptanos (6%) e drogas antiinflamatórias esteroidais (12%). Houve uma diminuição significativa da duração da dor e menor interferência da cefaleia nas atividades dos pacientes após o uso dos analgésicos. Conclusão : Prevalência da cefaleia por uso excessivo de medicamento (CEM) vem aumentando em nível populacional e em serviços especializados. Novos estudos enfatizando a CEM são necessários para auxiliar na melhora da sua abordagem diagnóstica e terapêutica. .


Subject(s)
Adolescent , Adult , Aged , Female , Humans , Male , Middle Aged , Young Adult , Analgesics/therapeutic use , Headache Disorders, Secondary/epidemiology , Migraine Disorders/drug therapy , Migraine Disorders/epidemiology , Brazil/epidemiology , Chronic Disease , Leisure Activities , Pain Measurement , Pain Clinics/statistics & numerical data , Quality of Life , Self Medication , Sex Distribution , Surveys and Questionnaires , Time Factors , Work
16.
Rev. méd. Chile ; 143(1): 47-55, ene. 2015. tab
Article in Spanish | LILACS | ID: lil-742550

ABSTRACT

Background: Health care workers are exposed to high stress levels and psychosocial risks. The imbalance between the invested efforts and received rewards acquires special importance in this setting. Aim: To assess the psychosocial risk level and its relationship with depression, distress and psychotropic drug use among health care workers. Material and Methods: Seven hundred eighty two workers (602 females; 180 males) answered self-administered questionnaires to measure psychosocial risk and mental health. Results: Twenty five percent of respondents used psychotropic drugs, 34% had a high level of distress and 23% had depressive symptoms. They also reported a low level of decisional latitude (48%), high emotional demands (47%), low social support (41%) and a significant effort-reward imbalance (67%). Those exposed to job strain (high demands and low decisional latitude), iso-strain (job strain plus low social support), and effort-reward imbalance were twice as likely to suffer symptoms of depression and elevated distress compared to non-exposed subjects. Conclusions: There are high levels of psychosocial stress among health care workers.


Subject(s)
Aged , Female , Humans , Male , Middle Aged , Epilepsy/diagnosis , Epilepsy/epidemiology , Ischemic Attack, Transient/diagnosis , Ischemic Attack, Transient/epidemiology , Migraine Disorders/diagnosis , Migraine Disorders/epidemiology , Cohort Studies , Diagnosis, Differential , Emergency Service, Hospital/statistics & numerical data , Epilepsy/mortality , Ischemic Attack, Transient/mortality , Longitudinal Studies , Myocardial Infarction/epidemiology , Prevalence , Prognosis , Prospective Studies , Retrospective Studies , Risk Assessment , Stroke/epidemiology , Survival Rate , Time Factors
17.
Rev. Assoc. Med. Bras. (1992) ; 59(6): 589-593, nov.-dez. 2013. tab
Article in English | LILACS | ID: lil-697390

ABSTRACT

OBJECTIVE: To verify the association between depression and headache in young adults, as well as to identify the features of headache associated with depression and the influence of this mood disorder on headache-related disability. METHODS: A cross-sectional study with self-administered questionnaires about headache and depression was conducted at the Universidade de Caxias do Sul. Beck Depression Inventory (BDI) and Migraine Disability Assessment (MIDAS) were used to evaluate depressive symptoms and headache-related disability, respectively. Depression was considered if BDI > 15. RESULTS: A thousand and thirteen young adults were included in the study. A clear relationship was observed between headache and depression among the participants. Multivariate analyses demonstrated that nausea or vomiting related to headache and higher headacherelated disability scores were independent factors associated with depression. Migraine was more associated with depression than the other types of headache. CONCLUSION: The results demonstrate an association between headache and depression. Depressive symptoms are more likely to be found in young adults with more disabling headaches.


OBJETIVO: Verificar a associação entre depressão e cefaleia em adultos jovens, assim como identificar as características da cefaleia relacionadas com depressão e a influência da depressão na incapacidade decorrente da cefaleia. MÉTODOS: Estudo transversal com questionários autoadministrados sobre cefaleia e depressão foi conduzido na Universidade de Caxias do Sul. O Inventário de Depressão de Beck (BDI) e o questionário de avaliação da incapacidade por enxaqueca (MIDAS) foram utilizados para avaliação dos sintomas depressivos e incapacidade, respectivamente. Depressão foi definida como BDI > 15. RESULTADOS: Foram incluídos no estudo 1.013 adultos jovens. Observou-se uma clara relação entre cefaleia e depressão entre os participantes. Análisesmultivariadas demonstraramque náuseas ou vômitos relacionados à cefaleia e incapacidade decorrente da dor foram fatores independentes associados à depressão. Enxaqueca foi mais associada com depressão que os outros tipos de cefaleia. CONCLUSÃO: Os resultados demonstram associação entre cefaleia e depressão. Sintomas depressivos são mais comuns em adultos jovens com cefaleias mais incapacitantes.


Subject(s)
Adolescent , Adult , Female , Humans , Male , Young Adult , Depressive Disorder/complications , Headache/psychology , Age Distribution , Brazil/epidemiology , Cross-Sectional Studies , Depressive Disorder/epidemiology , Headache/epidemiology , Migraine Disorders/complications , Migraine Disorders/epidemiology , Prevalence , Surveys and Questionnaires
18.
Cad. saúde pública ; 29(9): 1877-1888, Set. 2013. tab
Article in Portuguese | LILACS | ID: lil-686773

ABSTRACT

Estimou-se a prevalência de doenças crônicas diagnosticadas e de problemas de saúde referidos em adolescentes, segundo variáveis sociodemográficas e estado nutricional. É um estudo transversal de base populacional com dados do Inquérito de Saúde do Município de Campinas, São Paulo, Brasil, 2008. Foram utilizadas estatísticas descritivas, teste de associação pelo χ². A prevalência de doença crônica entre os adolescentes foi de 19,17%, asma apresentou a maior prevalência 7,59%, seguida de doenças cardíacas 1,96%, hipertensão 1,07% e diabetes 0,21%. A prevalência de problemas de saúde foi de 61,53%, alergia 40,39% e dor de cabeça frequente/enxaqueca 24,83% foram mais frequentes. Após análise múltipla por regressão de Poisson os fatores associados à doença crônica foram faixa etária de 15 a 19 anos (RP = 1,38), não frequentar escola (RP = 1,46), ter filhos (RP = 1,84) e ser obeso (RP = 1,54), e somente sexo feminino (RP = 1,12) se associou a problemas de saúde. A adolescência é uma fase da vida na qual também se adoece.


We estimated the prevalence of chronic diseases and other health problems reported by adolescents in relation to social and demographic variables and nutritional status. This cross-sectional population-based survey analyzed data from the Health Survey in Campinas, São Paulo State, Brazil, 2008. We used descriptive statistics and associations between variables with the chisquare test. Prevalence of chronic diseases among adolescents was 19.17%, with asthma showing the highest prevalence (7.59%), followed by heart disease (1.96%), hypertension (1.07%), and diabetes 0.21%. Prevalence rates were 61.53% for health problems, 40.39% for allergy, and 24.83% for frequent headache or migraine. After multivariate analysis using Poisson regression, the factors associated with chronic disease were age 15 to 19 years (PR = 1.38), not attending school (PR = 1.46), having children (PR = 1.84), and obesity (PR = 1.54). Female gender (PR = 1.12) was statistically associated with health problems. The study illustrates that adolescence is a life stage in which chronic disease and health problems can occur.


Se estimó la prevalencia de enfermedades crónicas y problemas de salud informados por los adolescentes, de acuerdo con las variables sociodemográficas y su estado nutricional. Se trata de un estudio transversal de base poblacional con datos de la Encuesta de Salud de Campinas, São Paulo, Brasil, 2008. Se utilizó estadística descriptiva con el test de asociación de χ². La prevalencia de enfermedad crónica entre adolescentes fue de un 19,17%, el asma presentó la mayor prevalencia un 7,59%, seguido por la enfermedad cardíaca un 1,96%, hipertensión un 1,07% y la diabetes un 0,21%. La prevalencia de problemas de salud fue de un 61,53%, la alergia un 40,39% y frecuentes dolores de cabeza/migraña un 24,83% fueron los problemas de salud más frecuentes. Tras el análisis multivariante, mediante la regresión de Poisson, los factores asociados con la enfermedad crónica tenían entre 15 y 19 años (RP = 1,38), no asisten a la escuela (PR = 1,46), tienen hijos (RP = 1,84) y obesidad (RP = 1,54), y sólo el sexo femenino (RP = 1,12) se asoció con problemas de salud. La adolescencia es una etapa de la vida en la que también se enferma.


Subject(s)
Adolescent , Child , Female , Humans , Male , Pregnancy , Young Adult , Chronic Disease/epidemiology , Asthma/epidemiology , Brazil/epidemiology , Cardiovascular Diseases/epidemiology , Chronic Disease/classification , Epidemiologic Methods , Headache/epidemiology , Migraine Disorders/epidemiology , Socioeconomic Factors , Urban Population
19.
Arq. neuropsiquiatr ; 71(2): 87-91, Feb. 2013. tab
Article in English | LILACS | ID: lil-663914

ABSTRACT

OBJECTIVE: The pathophysiology of migraine and restless legs syndrome (RLS) seems to involve inherited mechanism and dysfunction of the dopaminergic system. Previous articles have shown that the frequency of RLS is higher in migraine patients than in controls. We conducted a study to evaluate comorbidities, medication used and depressive symptoms that can explain the relation between migraine and RLS. METHODS: A case-control study was performed in which patients with migraine (n=72) and a control group without migraine (n=72) were interviewed. Data including RLS diagnosis, depressive symptoms, comorbidities and drugs used were evaluated. RESULTS: There was a significant association between migraine and RLS (p=0.01), but comorbidities such as diabetes, hypertension, anemia and drugs used did not explain this association. Depression scores, as measured by the Beck Depression Inventory, were higher in migraine patients with RLS (p =0.04). CONCLUSION: No specific factors explaining the association between migraine and RLS were found. Symptoms of depression were more frequent in patients with migraine and RLS.


OBJETIVO: A fisiopatologia da enxaqueca e da síndrome das pernas inquietas (SPI) parece envolver mecanismos genéticos e disfunção do sistema dopaminérgico. Artigos anteriores mostraram que a frequência de SPI em pacientes com enxaqueca é maior do que nos controles. Desenvolvemos um estudo para avaliar comorbidades, medicamentos utilizados e sintomas depressivos em pacientes com migrânea e SPI. MÉTODOS: Foi desenvolvido um estudo de caso-controle. Foram entrevistados pacientes com enxaqueca (n=72) e sujeitos de um grupo controle (n=72). Foram avaliados dados incluindo diagnóstico de SPI, sintomas depressivos, comorbidades e medicamentos usados. RESULTADOS: Houve associação significativa entre enxaqueca e SPI (p=0,01). Comorbidades como diabetes, hipertensão, anemia ou drogas utilizadas não explicam esta associação. Escores de depressão, medidos pelo Inventário de Beck, foram mais altos em pacientes com enxaqueca e SPI (p=0,04). CONCLUSÃO: Não foram encontrados fatores específicos que explicam a associação entre enxaqueca e SPI. Sintomas de depressão foram mais frequentes em pacientes com enxaqueca e SPI.


Subject(s)
Adolescent , Adult , Aged , Female , Humans , Male , Middle Aged , Young Adult , Migraine Disorders/epidemiology , Restless Legs Syndrome/epidemiology , Age Distribution , Brazil/epidemiology , Comorbidity , Depression/epidemiology , Depression/psychology , Epidemiologic Methods , Migraine Disorders/drug therapy , Migraine Disorders/psychology , Personality Inventory , Restless Legs Syndrome/drug therapy , Restless Legs Syndrome/psychology , Sex Distribution
20.
Gut and Liver ; : 668-674, 2013.
Article in English | WPRIM | ID: wpr-209560

ABSTRACT

BACKGROUND/AIMS: Migraine is frequently accompanied by symptoms consistent with functional gastrointestinal disorders (FGIDs). This study evaluated the prevalence of functional gastrointestinal symptoms and assessed the symptoms' relationship with the concomitant functional symptoms of anxiety, depression, and headache-related disability. METHODS: This prospective study included 109 patients with migraine who were recruited from a headache clinic at a teaching hospital. The participants completed a self-administered survey that collected information on headache characteristics, functional gastrointestinal symptoms (using Rome III criteria to classify FGID), anxiety, depression, and headache-related disability. RESULTS: In total, 71% of patients met the Rome III criteria for at least one FGID. In patients with FGID, irritable bowel syndrome was the most common symptom (40.4%), followed by nausea and vomiting syndrome (24.8%) and functional dyspepsia (23.9%). Depression and anxiety scores were significantly higher in patients meeting the criteria for any FGID. The number of the symptoms consistent with FGID in individual patients correlated positively with depression and anxiety. CONCLUSIONS: FGID symptoms defined by the Rome III criteria are highly prevalent in migraine. These symptoms correlate with psychological comorbidities, such as depression and anxiety.


Subject(s)
Adolescent , Adult , Aged , Female , Humans , Male , Middle Aged , Young Adult , Anxiety/epidemiology , Comorbidity , Depression/epidemiology , Disability Evaluation , Dyspepsia/epidemiology , Gastrointestinal Diseases/epidemiology , Migraine Disorders/epidemiology , Nausea/epidemiology , Prevalence , Prospective Studies , Republic of Korea , Vomiting/epidemiology
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